Domains and motifs--proteins in bite-sized chunks
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چکیده
منابع مشابه
Tutorial section: Domains and motifs - proteins in bite-sized chunks
Possibly the ultimate goal of bioinformatics is to be able to predict protein tertiary structure and chemical functionality from the initial amino acid sequence. Despite the best efforts of many researchers over the past two decades, a reliable modelling method has yet to be found and the folding problem continues to be a hurdle for scientists.
متن کاملTOPDOM: database of conservatively located domains and motifs in proteins
UNLABELLED The TOPDOM database-originally created as a collection of domains and motifs located consistently on the same side of the membranes in α-helical transmembrane proteins-has been updated and extended by taking into consideration consistently localized domains and motifs in globular proteins, too. By taking advantage of the recently developed CCTOP algorithm to determine the type of a p...
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متن کاملTOPDOM: database of domains and motifs with conservative location in transmembrane proteins
UNLABELLED The TOPDOM database is a collection of domains and sequence motifs located consistently on the same side of the membrane in alpha-helical transmembrane proteins. The database was created by scanning well-annotated transmembrane protein sequences in the UniProt database by specific domain or motif detecting algorithms. The identified domains or motifs were added to the database if the...
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ژورنال
عنوان ژورنال: Briefings in Bioinformatics
سال: 2004
ISSN: 1467-5463,1477-4054
DOI: 10.1093/bib/5.1.71